Although CMS sent a memo to state Medicaid directors about this designation in 2016 (CMS, 2016e) and updated Chapter 16B of the Medicare Managed Care Manual (CMS, 2016b) to include more description of the category, few of the states or plans with which we spoke during our case studies or at our in-person meeting reported that they understood how these plans worked or why it might be beneficial for them to pursue this designation
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Biological aging involves: Collagen degradation Chronic low-grade inflammation (inflammaging) Reduced cellular repair Muscle decline Connective tissue degeneration Mitochondrial dysfunction Slower wound healing Oxidative stress accumulation GHK-Cu has attracted attention because studies suggest it may influence several of these pathways simultaneously
Yenugu, S., Hamil, K.G., French, F.S., and Hall, S.H., Reprod
A., Metz, M
