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Experimental models and human data established two main theories underlying AD, the accumulation of toxic amyloid (A) peptides, characteristic of senile plaques, and the aggregation of tau protein, a microtubule-associated protein expressed in neurons that is involved in the stabilization of microtubules in the cytoskeleton

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The AAPS journal, 17(1), 134143

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References Ali A, Naz A, Soares SC, Bakhtiar M, Tiwari S, Hassan SS, Hanan F, Ramos R, Pereira U, Barh D, Figueiredo HCP, Ussery DW, Miyoshi A, Silva A, Azevedo V (2015) Pan-genome analysis of human gastric pathogen H