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It also positively upregulated VD regulatory genes ( VDBP /VD-25-hydroxylase/ VDR ) in the liver and glucose metabolism genes (PGC-1/VDR/GLUT-4) in muscle, boosted 25(OH)VD, and reduced inflammation and insulin resistance (IR) levels in the blood compared with supplementation with VD alone

doi: 10.1105/tpc.107.051383

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