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High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells

The organ damages following hyperglycemia/ROS stress can be hindered by initiating good glycemic control very early, but is not easily reversed if poorly handled over a longer time period 19

Galectin-3 Expression Is Prognostic In Diffuse Type Gastric Adenocarcinoma Confers Aggressive Phenotype And Can Be Targeted By YAP1/BET Inhibitors

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Isolation and protection mechanisms: barrier function of lipid droplets in preventing lipotoxicity High levels of saturated fatty acids, particularly palmitate, may incorporate directly into the mitochondrial membrane and trigger a lipotoxic response