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This minimal configuration also explains the efficient transport of -aminolevulinic acid, which serves as a precursor for the endogenous porphyrin accumulation on which photodynamic therapy of tumors is based

MCT1 consists of 12 TM -helical domains with a large intracellular loop between TM segments VI and VII and intracellular C- and N- termini (Poole et al

Though the concept of a healthy microbiota is challenging to define, dysbiosis can usually be defined as a certain imbalance where the pathogenic species are dominant over beneficial symbionts and commensals (Hou et al

doi:10.1006/jmbi.1993.1376

It has gained significant attention for its regenerative, anti-inflammatory, and angiogenic properties