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Curr Alzheimer Res 2(2):131136 Ringman JM, Frautschy SA, Teng E, Begum AN, Bardens J, Beigi M, Gylys KH, Badmaev V, Heath DD, Apostolova LG, Porter V, Vanek Z, Marshall GA, Hellemann G, Sugar C, Masterman DL, Montine TJ, Cummings JL, Cole GM (2012) Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study

39 Many physiological processes require iron, but iron overload produces toxic effects because excessive free iron can easily change between trivalent and bivalent forms

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36 Furthermore, depression results from some pathways, including chronic inflammation, formation of serotonin, expression of mitochondrial proteins, Ca 2+ homeostasis, and antioxidant gene expression, 37 which are indirectly related to vitamin D

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