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Furthermore, cellular senescence and the SASP exacerbate chronic inflammation and glial dysfunction, with sex differences and lipid metabolism playing modulating roles

The syringe that added water has been in contact with the bacteriostatic water vial stopper and potentially your fingers during the process

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Although direct in-patient persister identification is still technically challenging, in vivo and ex vivo biofilm models (rodent catheter and denture models, tissue explants) replicate biofilm architecture and have been used to show treatment failure and regrowth consistent with persister-mediated relapse (Wuyts et al., 2018