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The biological half-life of exogenous melatonin in humans is short, ranging from 10 to 60 minutes

The intestinal barrier is a selective barrierits function is to allow the transport of digested food essential for the bodys function, but at the same time to keep harmful substances and microorganisms in the intestinal lumen, which requires strict regulation of the barriers permeability [9, 19]

PMID: 37364590

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Mechanism and effects Pinealon influences gene expression related to circadian rhythm and melatonin synthesis, potentially optimizing sleep-wake cycles that profoundly impact cognitive function