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BPC-157 (Body Protection Compound-157) is a synthetic peptide fragment derived from a naturally occurring protein in gastric juices

A synthetic method of Cagrilintide is characterized by comprising the following steps: selecting 7-8 th amino acid of a Cagrilintide sequence as a pseudo-pro dipeptide Fmoc-Ala-Thr (pro-me-me) -OH, taking 10-11 th amino acid of the Cagrilintide sequence as a pseudo-pro dipeptide Fmoc-Ala-Thr (pro-me-me) -OH, and taking 21-22 th amino acid of the Cagrilintide sequence as a pseudo-pro dipeptide Fmoc-Ser-Ser (pro-me-me) -OH

BPC-157 is a stable gastric pentadecapeptide originally derived from human gastric juice, while TB-500 is a synthetic peptid

Randomization was stratified by HbA1c of less than 85% at screening (yes or no) and country (Japan

202 SchweighauserM.ShiY.TarutaniA.KametaniF.MurzinA