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Additional information Handling Editor: Subha Narayan Rath

Phase 1 multicenter dose-escalation study of ezatiostat hydrochloride (TLK199 tablets), a novel glutathione analog prodrug, in patients with myelodysplastic syndrome

On the day of the assays the material was slowly thawed at 4C

Yan LJ, Allen DC

To address these issues, improved formulations have been developed, such as the L-asparaginase variant ABD-ErA-TM, designed by Van Trimpont et al., which has shown reduced toxicity in mouse models [125]