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Oxidative stress disrupts tissue and organ function, ultimately causing systemic dysfunction [5]

Frontiers in Bioscience (Landmark Ed), 15 , 166179

doi: 10.1152/ajpendo.1999.277.3.E551

References: Katzung BG (2021): Introduction to Autonomic Pharmacology (Chapter 6)

The addition of oxygen during HMP is aimed at reducing ischaemiareperfusion injury, but has shown mixed results in kidney transplantation, often depending on the duration of perfusion, although some studies found that the addition of oxygen improved outcomes in higher-risk donors