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Perera, R

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Kidney Dis (Basel) 6:395406 Adema AY, de Roij van Zuijdewijn CLM, Hoenderop JG, de Borst MH, Ter Wee PM, Heijboer AC, Vervloet MG, NIGRAM consortium (2018) Influence of exogenous growth hormone administration on circulating concentrations of -klotho in healthy and chronic kidney disease subjects: a prospective, single-center open case-control pilot study

Subcutaneous injection produces a half life closer to three hours because the peptide enters circulation gradually through capillary absorption, bypassing immediate hepatic degradation

GHK-Cu increases vascular endothelial growth factor expression, promoting capillary density and blood vessel formation in healing wounds