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In chondrocyte cultures, GHK-Cu increased the expression of type II collagen, the main structural protein of hyaline cartilage, as well as aggrecan, the most important proteoglycan for the compressive resistance of articular cartilage

Nonetheless, NAPQI binding to mitochondrial proteins correlates with APAP toxicity30, and hence the effect could be a cumulative one, with mitochondrial function being affected once a threshold of mitochondrial protein modification is attained

Gender and the Parkinsons disease phenotype