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2F) likely from the loss of conformational freedom in the peptide when multiple histidine residues are tied to the same metal-ion

For example, temperature will be close to the freezing point, and, for microorganisms at the ice-ocean interface, salinities could also be high as dissolved salts are excluded from forming ice (Buffo et al., 2020)

We showed that the injection of fibroblasts could maintain the IVD height and rescue IVD signals in cynomolgus monkeys