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The major difference between STM and AFM is in the basic principles of their operation, where STM measures a tunneling current between a conductive tip and sample (thus being limited to the analysis of conductive and semiconducting samples), whereas AFM measures forces, such as van der Waals forces, between a tip and the surface and can be used for analysis of any material, conductive or not

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Grazoprevir, glecaprevir, and voxilaprevir are all NS3/4A protease inhibitors, which are contraindicated in patients with decompensated cirrhosis because of the risk of worsening hepatic decompensation