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However, these compounds have a short half-life, undergo rapid oxidation, and their HS release is uncontrolled

doi: 10.3389/fphar.2025.1737199 Received 01 November 2025 Revised 21 December 2025 Accepted 29 December 2025 Published 15 January 2026 Volume 16 - 2025 Edited by Dawei Chen, University of Kiel, Germany Reviewed by Eveljn Scarian, University of Pavia, Italy Hong Cheng, Yangzhou University, China Updates Copyright 2026 Knudsen, Tadje, Coggins and Venketaraman

Tiwari R, Latheef SK, Ahmed I, Iqbal HM, Bule MH, Dhama K, et al

[DOI] [PubMed] [Google Scholar] 42.Feldstein A.E., Werneburg N.W., Canbay A., Guicciardi M.E., Bronk S.F., Rydzewski R., Burgart L.J., Gores G.J

Studies show that combining topical and oral glutathione delivers superior results than a single treatment method