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Diabetic painful and insensate neuropathy: pathogenesis and potential treatments

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While measurement of LPS in healthy individuals is difficult due to its low levels and issues with contaminated lab equipment, inhibition of LPS-receptor, the toll-like receptor 4 (TLR4), reduces blood pressure (BP) and inflammatory markers (e.g., IL6, macrophage infiltration to the kidneys) in experimental models of hypertension [17, 18]

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Stem Cells International , 2019 (1), 8036035

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However, there is a growing need to develop advanced nanoformulations for targeted delivery and enhanced efficacy

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