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Thus, while IN chelation is promising for directly targeting the brain and CNS, it still requires careful consideration of formulation strategies (e.g., nanoparticle targeting or controlled-release systems) to improve site specificity, especially for drugs with a narrow therapeutic window

Some patients may notice better digestion

Hsu et al., 2019), may not necessarily compete with MAD, but instead could be also integrated through common pathways

The most common issues are slight injection site irritation and occasional headaches

Studies have shown that oral supplements of B12 and injections both offer effective treatment of deficiencies