It modulates multiple biological processes simultaneously
The growth-promoting effects of growth hormone include muscle tissue hypertrophy (which may be desired by some but represents an anabolic effect), bone growth and remodeling (problematic after growth plates close), organ enlargement with chronic supraphysiologic doses (cardiac hypertrophy, acromegaly features), connective tissue proliferation (potentially contributing to joint pain and carpal tunnel syndrome), and cellular proliferation that may support tumor growth in susceptible individuals
Some preclinical studies suggest BPC-157 may work with physical therapy, platelet-rich plasma (PRP), or growth factors, but combination studies in humans are still lacking
Choose a site proximal to the injured tendon, either subcutaneously in the overlying skin or intramuscularly in the adjacent muscle belly, to maximize local peptide concentration at the repair zone
They were then fixed in formalin and processed for histologic and histochemical evaluation and morphometry