A negatively charged side chain from DHKs aspartic acid residue replaces glycine or alanine in other variations, which may affect copper binding and cell membrane interactions
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IM's shorter duration (34 hours) would create significant trough periods between doses, requiring either more frequent injections or accepting subtherapeutic windows
J Clin Psychopharmacol 26:524529 Pross N, Patat A, Vivet P, Bidaut M, Fauchoux N (2015) Pharmacodynamic interactionsof a solid formulation of sodium oxybate and ethanol in healthy volunteers
Copper peptides help neutralise free radicals, reducing oxidative stress and preventing additional skin damage