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Several human studies have demonstrated that supplementing standard-of-care chemotherapies (such as cisplatin, doxorubicin, cyclophosphamide, and busulfan) with Se (in the form of sodium selenite or organic selenium) reduces toxicity without compromising therapeutic efficacy [310]

Most human study data does start on a lower dose of 100 to 200 milligrams of NMN, slowly working up to 500 milligrams, according to Jillian Robillard, MS, RD, LDN

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Researchers have classified it as a research peptide with a pleiotropic profile meaning it appears to interact with multiple biological pathways rather than acting on a single receptor