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Those with MCI have greater risk of conversion to AD than the normal population, with conversion rates ranging from 10 to 36% over a 2-year period depending on the methods used and the population under study [5]

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ME/CFS, FM, and GWS were selected for this review due to (i) the common overlap of ME/CFS and FM where similar biological dysfunction might be expected and (ii) GWS, with its identifiable and specific trigger, likely to offer a different biological perspective