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However, as we age, NAD+ levels decline, leading to fatigue, brain fog, and slower recovery

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The results of a sequential supplementation trial in 53 men and women indicated that after optimization of folate status with folic acid supplements, vitamin B 12 became the major determinant of plasma homocysteine levels (30)

Strong AP, Haeusler S, Weatherall M, Krebs J (2016) Sublingual vitamin B12 compared to intramuscular injection in patients with type 2 diabetes treated with metformin: a randomized trial