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Recent study also demonstrated that progressive resistance training, an exercise intervention, increased the abundances of dehydroepiandrosterone sulfate (DHEAS), and change in DHEAS levels reversely associated with the improvement of fatigue scores (123)

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In this situation, it can be challenging to demonstrate B12 deficiency even when there are typical symptoms (including neuropathy-like paraesthesia and numbness), as serum B12 concentrations may be just within, or sometimes above, the normal range due to the oral supplementation

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