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Nephron Clin Pract (2010) 115(2):c15460

Stress and Hormone Modulation: Evidence suggests DSIP may regulate cortisol, growth hormone, and other neuroendocrine pathways, contributing to stress reduction and recovery

The data consistently shows measurable changes beginning around week 4 and becoming significant by week 8 to 12

Immunoreactivity assays for endogenous DSIP-like material in tissue and CSF have used antibodies whose specificity for the nonapeptide versus related peptides has not always been rigorously established (Kovalzon & Strekalova, 2006)