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The clinical applications of such findings are obvious as much they may identify patients who will benefit from combination of anti-TNFs with immunomodulators or who should better receive non-anti-TNF- therapies

BCAT1, along with bone marrow stromal antigen 2 (BST 2) and the tyrosine kinase MERTK, promotes cancer progression by regulating TAM 2 polarization, offering a potential target for pancreatic cancer treatment

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LAT1 is a transmembrane amino acid transporter responsible for transporting large neutral amino acids such as leucine, isoleucine, valine, phenylalanine, and tyrosine from outside the cell to the inside