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Observed variability could be due to intrinsic variability of synapses (e.g., of the ratios of NMDA/AMPA receptors and calcium permeable/impermeable AMPA receptors across synapses within the same type of connection) and also to differences in experimental conditions and plasticity induction protocols (see Box 3 and Table 1) as well as animal lines and age and possible biases in sampling of highly heterogeneous inhibitory neurons

Is L-Arginine itself an active component in this formulation

Conclusion: Sublingual and oral B12 supplementation appear to be as effective as intramuscular (IM) injections in improving cobalamin status and reducing homocysteine levels

Interestingly, PD patients show significantly reduced glutathione levels in the SN [126], suggesting a compromised PPP flux as a factor of PD oxidative stress

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