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Acknowledgments The authors gratefully acknowledge the support of Sidra Medicine, Qatar, for providing institutional resources that facilitated this review

Homocysteine can be measured with a simple blood test, and optimal levels are generally considered to be below 10 mol/L

Collection and preparation of plasma, liver, and kidney specimens for metabolomics Blood was obtained via cardiac puncture and centrifuged at 3000 g at 4 C for 10 min

To obtain an Ab aqueous extract rich in bioactive substances such as carbohydrates, in special -glucans, proteins and phenolic compounds ( in vivo (135 mg/Kg) and in vitro experiments (2.81 and 22.5 mg/mL)

Individuals are biomarkerpositive and have dementia symptoms with mild functional impairment