Their unpaired electrons can wreak havoc on our cells, leading to oxidative stress, inflammation, chronic diseases, and even cancer
Here we demonstrate that acute brain injury induces vascular damage, meningeal cell death, and the generation of reactive oxygen species (ROS) that ultimately breach the glial limitans and promote spread of the injury into the parenchyma
Human MTs can be classified into four classes, namely MT1 to MT4, comprising a total of eleven functional isoforms, with eight of them belonging to class 1
FOXO4-DRI enters senescent cells and competitively binds to p53 through its modified peptide sequence, displacing endogenous FOXO4 and freeing p53 to activate cell death pathways including BAX and PUMA
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