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Cardiovascular disease When combined with folate and B6, vitamin B12 can reduce homocysteine levels, which may offer benefit for cardiovascular disorders, although results from studies are mixed

In addition to the lean and ob/ob mice, the study included 3-KO mice and WT controls obtained from genetically verified breeding colonies

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Gastric acid and pepsin in the stomach release B12 from these dietary proteins, allowing it to bind with R-proteins (haptocorrins) secreted in saliva