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Approximately 70 percent of GPX3 is secreted by the basolateral membrane of renal proximal convoluted tubule (PCT) cells and into plasma through the basilar artery (Zhao et al., 2019

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In addition, acetaminophen exposure itself induces increased CYP2E1, thus increasing the amount of NAPQI formed with each exposure to the drug.Posadas et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] 74.Klamkam P., Pagcharoenpol R., Treesaranuwattana T., Silpsrikul P., Jaruchinda P., Wasuwat P., Suwannahitatorn P