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Although Roche discontinued the brand-name Accutane in 2009 due to declining market share, generic versions of Isotretinoin are still commonly prescribed today, underscoring that Isotretinoin has been used to treat acne for over 43 years

Due in part to the great diversity of molecules that can be metabolized by CYPs, the rate of these reactions can vary greatly, with exogenous compounds like drugs exhibiting slower catalytic rates compared to endogenous molecules

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Development of data-independent acquisition workflows for metabolomic analysis on a quadrupole-orbitrap platform

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