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Thats especially the case for those containing hydroquinone, which you can read more about here

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Nonetheless, our modeling study [10] showed that the model results compare well to several experimental and clinical studies (figure 2, figure 6, figure 13 in [10] )

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Several studies showed evident association between type II diabetes and cancer, in particular in liver and pancreas, organs persistently exposed to high levels of endogenous insulin 117,118,119