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BPC-157 was well-tolerated and exhibited no severe toxic effects in mice, rats, rabbits, and dogs

Since adipose tissue is responsive to endotoxins, bacterial translocation may provide a mechanism whereby the gut microbiome can modulate the adipose metabolome (for review, Kruis et al., 2014 23 ) and consequently exacerbate obesity and its related comorbidities

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Authors have reported mild and temporary skin reactions at the injection site, such as redness, itching, or swelling