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Though Citral has documented antimicrobial activity against acne bacteria (which is where the marketing claims about it being good for acne-prone skin originate), real formulas use it at fragrance-level concentrations under 1% so there's likely no skin benefit

Here, the percentage of annexin V/7-AAD double-negative cells was normalized within each dose and biological replicate to the corresponding vehicle-treated control

They bind the GHRH receptor on pituitary cells and stimulate GH synthesis and release

In a letrozole-induced PCOS rat model, DCI (50 mg/kg) alone or in combination with Ecklonia cava extract (250 mg/kg) significantly reduced pro-inflammatory cytokine TNF- and IL-6 levels, attenuating systemic inflammation (61)

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