Low folate levels are found in up to 38% of patients with depression , and supplementation has been shown to enhance the effectiveness of antidepressants, with one study reporting a 93.3% improvement rate
[DOI] [PubMed] [Google Scholar] Rauh VA, Garfinkel R, Perera FP, Andrews HF, Hoepner L, Barr DB, Whitehead R, Tang D, Whyatt RW
Additionally, it is third-line therapy for patients with recalcitrant scalp psoriasis with minimal involvement of other sites
However, some causes of joint pain require treatment, such as when the pain results from injury or disease
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