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Although a clear mechanistic perspective is lacking, it can be conceptualized that gut microbial dysbiosis (and its metabolites) modulates innate and adaptive immune players by recruiting immune secreting cells from the appendix, thereby priming the immune system for an enhanced inflammatory response and a possible source of -synuclein misfolding (Masahata et al., 2014

GHK could form the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu 2+ (GHK-Cu) by the good affinity for Cu(II), which proved to exhibit good antioxidant and anti-inflammatory capabilities (Pickart, 2008)

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Central Retinal Artery Occlusion-A New, Provisional Treatment Approach