63 They secrete proinflammatory chemokines and cytokines such as monocyte chemotactic protein 1 (MCP-1), 64 prostaglandin E2 (PGE2), 65 interleukin 1 (IL-1), 66 IL-6, 67 IL-10, 67 tumor necrosis factor (TNF) and regulated on activation normal T cell expressed and secreted (RANTES)
However, parsley polyphenols demonstrated the most potent nitric oxide scavenging activity, which is essential in inflammation due to the overproduction of nitric oxide
doi: 10.1074/jbc.M110244200 32 Guerrero-BeltrnCECaldern-OliverMPedraza-ChaverriJChirinoYI
Atkins MB, Mier JW, Parkinson DR, Gould JA, Berkman EM, Kaplan MM
The two primary pathways activated are the PI3K/Akt/mTOR pathway and the MAPK pathway