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[33] These are thought to be due to defective DNA synthesis inhibiting replication in tissue sites with a high turnover of cells

Methionine plays a role in breaking down fats, helping to prevent the buildup of fatty deposits in blood vessels that might cause coronary artery disease and blockages in the neck and legs

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Diets high in sulfur foodstuffs or water or a combination of the two can also lead to thiamine deficiency

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