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Damage to nerve tissue (peripheral neuropathy), leading to pain, numbness, and weakness in extremities: These can be caused by the vitamins role in the proper functioning of the nervous system

A controlled study (PMID: 7777652) found that DSIP did not significantly affect CRH- or meal-induced ACTH and cortisol secretionindicating DSIP does not measurably blunt the human cortisol response, contrary to stress-protective effects suggested by some animal studies

These authors reported that such epigenetic factors could explain 11.6% of the variance in serum UA, substantially greater than the 7.7% explained by genetic variability alone

Vitamin C Vitamin C is a known partner for glutathione

10.1523/JNEUROSCI.3611-05.2006 J