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Although several researchers focused on biomedical applications on various hybrid NPs, environmental degradation is poorly investigated

Environmental sensitivity: protect from light and unnecessary temperature swings to help maintain integrity during storage

In a study in the 5XFAD mouse model of AD, microbial dysbiosis was noted to be associated with activation of the endolysosomal CCAAT/enhancer-binding protein- (C/EBP-) asparagine endopeptidase (AEP) pathway (Chen et al., 2020)

For those with neurological concerns: B12 supports nerve health, reducing the risk of neuropathy

Additionally, the gene changes include upregulation of cancer-protective genes and DNA repair mechanisms, suggesting a net protective effect