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Interestingly, in a rat model of lysolecithin demyelination, M2 depletion was associated with delayed oligodendrocyte differentiation and nodal reconstruction (Miron et al., 2013) suggesting the pro-myelinating role of M2 macrophages

Learned helplessness: validity and reliability of depressive-like states in mice

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One explanation for the detrimental effect of antioxidant treatment is that the exogenous antioxidants short-circuit the feedback mechanisms for initiating endogenous antioxidant response, feedback that includes accumulation of oxidative stress [56]