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Kong et al., similarly uncovered synergy between a complex I inhibitor and a mito-antioxidant in cancer cells, suggesting their ability to reduce mitochondria-derived H 2 O 2 levels as a potential mechanism of action ( 2 O 2 levels increased after 24 hours of (M+D)/2 and (M+D+V)/3 treatments

In several patients with BCS, protein C deficiency has also been associated with an underlying myeloproliferative disorder

Esophageal Varices Pathogenesis Local factors that determine the risk of hemorrhage from esophageal varices include the radius of the varix, the thickness of the varix wall, and the pressure gradient between the varix and the esophageal lumen