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Kato et al., 2023)

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Integration of 1 H NMR and UPLC-Q-TOF/MS for a comprehensive urinary metabonomics study on a rat model of depression induced by chronic unpredictable mild stress

While no direct clinical trials provide data on optimal human dosing of 6-gingerol for SLE, ginger extracts are generally regarded as safe, with human doses up to 2 grams daily (approximately 25 mg/kg for a 70 kg adult) showing good tolerability in other contexts (219)