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A reduced mitochondrial biogenesis through PGC-1/NRF1/TFAM (peroxisome proliferator-activated receptor- (PPAR- ) coactivator 1/nuclear respiratory factor-1/mitochondrial transcription factor A) was also observed [29]

Data Availability Statement The data supporting the findings of this study are available from the corresponding author upon reasonable request

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Metabolism [edit] GABA transaminase enzymes catalyze the conversion of 4-aminobutanoic acid (GABA) and 2-oxoglutarate (-ketoglutarate) into succinic semialdehyde and glutamate