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Bacterial contamination, even at low levels undetectable by visual inspection alone, introduces endotoxins that confound experimental results by triggering inflammatory responses independent of the peptide's intended mechanism

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This research is important to people with RA and their health care providers, and has potential to improve the quality of care and outcome of RA.

J Am Nutr Assoc 44(5):375386 Kuptniratsaikul V, Dajpratham P, Taechaarpornkul W, Buntragulpoontawee M, Lukkanapichonchut P, Chootip C, Saengsuwan J, Tantayakom K, Laongpech S (2014) Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study