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Nrf2 and autophagy Autophagy is a crucial cellular process involved in self-degradation, wherein cells maintain the organisms internal equilibrium by engulfing and degrading their own harmful or damaged organelles and proteins [118, 119]

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In the initial dose-finding studies, three concentrations of Cagrilintide ranging from 3, 30, and 300 nmol/kg, were tested in chow-fed WT mice