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It is not a protocol, not medical guidance, and not a suggestion that anyone administer these compounds

doi:10.1152/ajpregu.00360.2001

The escalation schedule built into the clinical protocol reflects the tolerability profile of combined receptor activation

In vivo imaging demonstrated that the B5-1@Cy5-siRNA subtype accumulates specifically in the lungs ( Figure 2E ), showing that different modifications lead to clear differences in organ distribution and enable selective targeting

This work was supported by grants from the National Institutes of Health (R00GM121856, R03AG067301, R35GM142495 and R35GM142495-02S1 to V.C