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REDEFINE 2: Efficacy in Type 2 Diabetes REDEFINE 2, announced in March 2025, addressed a distinct population: 1,206 adults with obesity or overweight and type 2 diabetes across 12 countries, randomised in a 3:1 ratio to CagriSema or placebo for 68 weeks

Bacteriostatic water for injection is supplied in a multiple-dose 30 mL plastic bottle and is not pressurized

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Topiramate may cause decreased sweating and increased body temperature (fever)