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Notably, in the condition of excess hemin exposure and hypoxia, our findings suggest an important contribution of the TSS pathway and its regulation by DMF for de novo cysteine synthesis and GSH generation in protecting against the oxidative and ferroptotic stresses in SCD erythroblasts

J Endocrinol Invest 124

Tyramine is found in fermented foods, like aged cheese and cured meats, as well as chocolate, non-pasteurized beer, and some wines

Despite observed evidence, corroborated by autopsy studies of ageing brains and those with neurodegenerative disorders, data from clinical trials is imperative to support the glutathione deficiency and oxidative stress theory of AD